| # | Children | Name | Born | Died | Father | Mother |
| 1 | | | b. Abt. Apr 1528 | d. Abt. 1528 | Henry Stewart, 1st Lord Methven, | Margaret Plantagenet Tudor, - Princess of England - Queen of Scotland - Countess of Angus |
| 2 | | | b. 8 Oct 1515 | d. 7 Mar 1578 | Archibald Douglas, 6th Earl of Angus | Margaret Plantagenet Tudor, - Princess of England - Queen of Scotland - Countess of Angus |
| 3 | | | b. 21 Feb 1507 | d. 27 Feb 1508 | James IV Stewart, King of Scotland | Margaret Plantagenet Tudor, - Princess of England - Queen of Scotland - Countess of Angus |
| 4 | | | b. 15 Jul 1508 | d. Aft. 15 Jul 1508 | James IV Stewart, King of Scotland | Margaret Plantagenet Tudor, - Princess of England - Queen of Scotland - Countess of Angus |
| 5 | | | b. 20 Oct 1509 | d. 14 July 1510 | James IV Stewart, King of Scotland | Margaret Plantagenet Tudor, - Princess of England - Queen of Scotland - Countess of Angus |
| 6 | | | b. 10 Apr 1512 | d. 14 Dec 1542 | James IV Stewart, King of Scotland | Margaret Plantagenet Tudor, - Princess of England - Queen of Scotland - Countess of Angus |
| 7 | | | b. Nov 1512 | d. Nov 1512 | James IV Stewart, King of Scotland | Margaret Plantagenet Tudor, - Princess of England - Queen of Scotland - Countess of Angus |
| 8 | | | b. 30 Apr 1514 | d. 18 Dec 1515 | James IV Stewart, King of Scotland | Margaret Plantagenet Tudor, - Princess of England - Queen of Scotland - Countess of Angus |